| ENZ-ABS731-0100 | 100 µl | 433.00 USD |  |
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| Alternative Name: | L-lactate dehydrogenase A chain, LDH1 |
| Clone: | AT1A4 |
| Host: | Mouse |
| Isotype: | IgG2bκ |
| Immunogen: | Recombinant human LDHA (aa 1-332) purified from E. coli. |
| UniProt ID: | P00338 |
| Source: | Purified from ascites. |
| Species reactivity: | Human |
| Applications: | ELISA, Flow Cytometry, ICC, IF, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein G affinity purified |
| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA is the predominant form in skeletal muscle and kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle. |
| Regulatory Status: | RUO - Research Use Only |
