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Bassoon monoclonal antibody (SAP7F407)

ENZ-ABS666-0050 50 µg 344.00 USD
ENZ-ABS666-0200 200 µg 729.00 USD
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Product Details

Immunogen:Recombinant rat Bassoon.
UniProt ID:O88778
Gene/Protein Identifier:29999 (UniGene)
Source:Purified from hybridoma tissue culture supernatant.
Species reactivity:Human, Mouse, Rat
Bovine, Dog
Applications:ICC, IF, IHC, IP, WB
Recommended Dilutions/Conditions:Immunocytochemistry (1:400)
Immunoprecipitation (2.5µg)
Western Blot (1:500 - 1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Bassoon is a 420 kDa protein that localizes at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors. These observations suggested that they serve specific functions at synaptic junctions and may be involved in organization of the cytoskeleton at the site of neurotransmitter release.
Regulatory Status:RUO - Research Use Only
Bassoon monoclonal antibody (SAP7F407) WB
Western Blot analysis of ENZ-ABS666: Lane 1: NovexTMHiMarkTM MW Marker, Lane 2: Mouse Brain lysate (Prod. No. ADI-LYT-MB100), Lane 3: Rat Brain lysate (Prod. No. ADI-LYT-RB100).
Bassoon monoclonal antibody (SAP7F407) IHC
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded rat brain tissue stained with Bassoon monoclonal antibody (SAP7F407), (Prod. No. ENZ-ABS666) at 10µg/ml.
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Bassoon monoclonal antibody (SAP7F407) WB Bassoon monoclonal antibody (SAP7F407) IHC

Product Literature References

Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membrane: M.L. Jobin, et al.; Nat. Commun. 14, 34 (2023), Abstract;
Immunohistochemical distribution of proteins involved in glutamate release in subepithelial sensory nerve endings of rat epiglottis: Y. Yamamoto, et al.; Histochem. Cell Biol. 157, 51 (2022), Abstract;

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