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United States 

FOLR1 (human) monoclonal antibody (548908)

ENZ-ABS378-0100 100 µg 658.00 USD
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Product Details

Alternative Name:Folate-binding protein, gp38, FRα, Folate Receptor α, Folate Receptor 1
Immunogen:Chinese hamster ovary cell line CHO derived recombinant human FOLR1 Arg25Met233.
UniProt ID:P15328
Species reactivity:Human
Crossreactivity:Does not cross-react with recombinant human FOLR2, 3 or 4 in direct ELISAs.
Applications:ELISA, Flow Cytometry, ICC, WB
Recommended Dilutions/Conditions:ELISA (0.1-0.4 µg/ml (Detection), 2-8 µg/mL (Capture))
Flow Cytometry (0.25 µg/106 cells)
Immunocytochemistry (8-25 µg/mL)
Western Blot (2 µg/mL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein A/G purified from hybridoma culture supernatant.
Formulation:Lyophilized from a 0.2 µm filtered solution in PBS with 5% Trehalose.
Reconstitution:Reconstitute at 0.5 mg/mL in sterile PBS.
Use/Stability:Stable one month reconstituted under sterile conditions at 4°C.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Short Term Storage:-20°C
Long Term Storage:-20°C
Scientific Background:The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid, several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Human FOLR1 shares 83% amino acid sequence identitiy with mouse and rat FOLR1. FOLR1 is up-regulated on many carcinomas, such as ovarian, and predominantly expressed on epithelial cells.
Technical Info/Product Notes:37 - 42 kDa protein
Regulatory Status:RUO - Research Use Only

Product Literature References

Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics: M.J. Pauwels, et al.; Biomaterials 290, 121830 (2022), Abstract;

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Folate receptor
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Folate receptor Monoclonal antibody
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