Alternative Name: | MN sialoglycoprotein, PAS-1, Sialoglycoprotein α, CD235a |
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Clone: | GYPA/1725R |
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Host: | Rabbit |
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Isotype: | IgGκ |
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Immunogen: | Recombinant human glycophorin A. |
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UniProt ID: | P02724 |
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Species reactivity: | Human
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Applications: | Flow Cytometry, IF, IHC (PS)
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Recommended Dilutions/Conditions: | Flow Cytometry (0.5-1 µg/106 cells in 0.1 mL) Immunofluorescence (0.5-1 µg/mL) Immunohistochemistry (formalin-fixed paraffin sections) (0.25-0.5 µg/mL for 30 min at RT) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | +4°C |
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Scientific Background: | Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). |
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Regulatory Status: | RUO - Research Use Only |
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