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PD-1 Recombinant monoclonal antibody (PDCD1/1410R)

 
ENZ-ABS348-0100 100 µg 554.00 USD
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Product Details

Alternative Name:Programmend cell death-1, CD279, Programmed death receptor 1
 
Clone:PDCD1/1410R
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:Recombinant human PD-1 protein fragment.
 
UniProt ID:Q15116
 
Species reactivity:Human
 
Applications:Flow Cytometry, IF, IHC (PS)
 
Recommended Dilutions/Conditions:Flow Cytometry (0.5-1 µg/106 cells in 0.1 mL)
Immunofluorescence (1-2 µg/mL)
Immunohistochemistry (formalin-fixed paraffin sections) (1-2 µg/mL for 30 min at RT)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.
 
Shipping:Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
 
Regulatory Status:RUO - Research Use Only
 

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