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CD20 Recombinant monoclonal antibody (RMC20-1)

 
ENZ-ABS346-0100 100 µg 466.00 USD
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Product Specification

Alternative Name:B-lymphocyte antigen CD20
 
Clone:RMC20-1
 
Host:Rabbit
 
Isotype:IgGκ
 
Immunogen:Full length human CD20.
 
UniProt ID:P11836
 
Species reactivity:Human
 
Applications:IHC (PS)
 
Recommended Dilutions/Conditions:Immunohistochemistry (formalin-fixed paraffin sections) (0.5-1 µg/mL) for 30 minutes at RT
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It has been shown that CD20 plays a role in the microenvironmental interactions of B cells. [Wiki]
 
Regulatory Status:RUO - Research Use Only
 

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