Alternative Name: | Hematopoietic progenitor cell antigen CD34 |
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Clone: | HPCA1/1806R |
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Host: | Rabbit |
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Isotype: | IgGκ |
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Immunogen: | Recombinant full length human CD34. |
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UniProt ID: | P28906 |
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Species reactivity: | Human, Rat
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Applications: | Flow Cytometry, IF, IHC (PS), WB
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Recommended Dilutions/Conditions: | Flow Cytometry (0.5-1 µg/106 cells in 0.1 mL) Immunofluorescence (2-4 µg/mL) Western blot (0.5-1 µg/mL) Immunohistochemistry (formalin-fixed paraffin sections) (2-4 µg/mL for 30 min at RT) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | +4°C |
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Scientific Background: | CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity. |
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Regulatory Status: | RUO - Research Use Only |
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