Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

ACTH Recombinant monoclonal antibody (r57)

 
ENZ-ABS319-0100 100 µg 408.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Adrenocorticotropic hormone, Corticotropin
 
Clone:r57
 
Host:Mouse
 
Isotype:lgG1
 
Immunogen:An N-terminal peptide (within aa 1-24) from the Synacthen/ACTH region of human POMC.
 
UniProt ID:P01189
 
Species reactivity:Human, Mouse, Rat
 
Specificity:This mAb is specific to Synacthen (aa 1-24 of ACTH); does not cross-react with CLIP (aa 17-39 of ACTH).
 
Applications:IHC (PS)
 
Recommended Dilutions/Conditions:Immunohistochemistry (formalin-fixed paraffin sections) (0.5-1 µg/mL) for 30 minutes at RT
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:ACTH (adrenocorticotropic hormone, corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, α-MSH (melanocyte stimulating hormone), β-MSH, γ-MSH, CLIP (corticotropin-like intermediary peptide), lipotropin-β, lipotropin-γ, β-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
 
Regulatory Status:RUO - Research Use Only
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
ACTH
By biological activity:
ACTH Recombinant antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Product Flyers
Recombinant Antibodies (rAb)
Recombinant Antibodies (rAb)
Download as PDF

All new literature pieces

Recommend this page

 
Keep in touch

©2020 Enzo Life Sciences, Inc.,