| ENZ-ABS314-0100 | 100 µg | 534.00 USD |  |
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| Alternative Name: | Melan-A, Melanoma antigen recognized by T cells 1 |
| Clone: | rMLANA/788 |
| Host: | Mouse |
| Isotype: | lgG1κ |
| Immunogen: | Recombinant full length human MART-1. |
| UniProt ID: | Q16655 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | Flow Cytometry, IF, IHC (PS), WB |
| Recommended Dilutions/Conditions: | Flow Cytometry (0.5-1 µg/106 cells in 0.1 mL) Immunofluorescence (0.5-1 µg/mL) Immunohistochemistry (formalin-fixed paraffin sections) (0.5-1 µg/mL for 30 min at RT) Western blot (0.5-1 µg/mL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
| Purity Detail: | Protein G affinity purified. |
| Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | +4°C |
| Scientific Background: | MART-1/Melan-A is a protein antigen that is found on the surface of melanocytes. The MART-1/Melan-A antigen is specific for the melanocyte lineage, found in normal skin, the retina, and melanocytes, but not in other normal tissues. It is thus useful as a marker for melanocytic tumors (melanomas) with the caveat that it is normally found in benign nevi as well. |
| Regulatory Status: | RUO - Research Use Only |
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