Product Details
| Alternative Name: | Glyceraldehyde-3-phosphate dehydrogenase |
| |
| Clone: | GA1R |
| |
| Host: | Mouse |
| |
| Isotype: | IgG1 |
| |
| Immunogen: | Full-length recombinant GAPDH. |
| |
| UniProt ID: | P04406 |
| |
| Species reactivity: | Human, Mouse, Rat
Chicken, E. coli, Hamster, Insect, Rabbit, Yeast
|
| |
| Specificity: | Recognizes GAPDH in multiple species, including human, mouse, rat, bacteria, chicken, hamster, insect, rabbit and yeast. |
| |
| Applications: | ELISA, Flow Cytometry, ICC, IF, IHC (PS), WB
|
| |
| Purity Detail: | Purified |
| |
| Formulation: | Liquid. In PBS containing a proprietary stabilizer and 0.02% sodium azide. |
| |
| Handling: | Do not freeze. |
| |
| Shipping: | Blue Ice Not Frozen |
| |
| Long Term Storage: | +4°C |
| |
| Scientific Background: | Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is an enzyme involved in glycolysis. In addition to this role, it is involved in other cellular processes ranging from membrane fusion, neuronal apoptosis to cancer. GAPDH is expressed at high levels in most tissues and is therefore useful as protein loading control in Western blot analysis. Additionally, the antigen is conserved in most eukaryotes. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Therapeutic gene correction for Lesch-Nyhan syndrome using CRISPR-mediated base and prime editing: G. Jang, et al.; Mol. Ther. Nucleic Acids
31, 586 (2023),
Abstract;
Endoplasmic reticulum-mitochondrial interaction mediated by Mitofusin-1 or Mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation: P.J. McFie, et al.; Biochem. Biophys. Res. Commun.
478, 392 (2016),
Application(s): Immunoblot analysis,
Abstract;
