| Alternative Name: | Amyloid A4 protein, Amyloid protein, ABPP, APPI, Amyloid beta A4 protein |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human APP. |
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| UniProt ID: | P05067 |
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| Source: | Purified from rabbit serum. |
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| Species reactivity: | Human, Mouse
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| Applications: | ELISA, IP, WB
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| Purity Detail: | Peptide affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Deposition of APP (Amyloid A4 protein) precursor intraneuronally as neurofibrillary tangles, extracellularly as plaques, and in blood vessels, is characteristic of both Alzheimer's disease and aged Down's Syndrome. There are five forms of APP: APP395, APP563, APP695, APP751, and APP770. They are produced by alternative splicing of the APP gene. APP695 is the most predominant form in neuronal tissue while APP751 is the predominant form found elsewhere. |
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| Regulatory Status: | RUO - Research Use Only |
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