5-Hydroxymethyluridine antibody recognizes 5-hydroxymethyluridine, which is created by the oxidation of thymine by ionising radiation or reactive oxygen species. This oxidation causes changes in gene expression, mutations, and chromosomal instability all of which play a role in cancer, autoimmune disease and aging. 5-hydroxymethyluridine is a potential biomarker for female breast, colon and rectal cancers, being present at elevated levels, possibly due to impaired DNA repair mechanisms.
Product Details
Host: | Goat |
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Immunogen: | 5-hydroxymethyluridine |
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Species reactivity: | Species independent
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Specificity: | Recognizes 5-hydroxymethyluridine. |
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Applications: | ELISA
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Recommended Dilutions/Conditions: | ELISA (1:25,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Formulation: | Liquid. Contains 0.09% sodium azide. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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