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Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use)

ENZ-30930 6 ml ~6 µg 256.00 USD
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Alternative size available: ENZ-C34930 (0.5ml)

Product Details

Immunogen:Human axillary lymph node tissue containing pigmented melanoma metastases.
Source:Purified from ascites.
Species reactivity:Human
Specificity:Recognizes a human melanoma-specific antigen present in melanocytic cells and junctional nevi.
Crossreactivity:Does not cross-react with normal melanocytes, intradermal nevus cells or other neoplasms including sarcomas, carcinomas and glial tumors.
Applications:IHC (PS)
Recommended Dilutions/Conditions:Immunohistochemistry (paraffin sections; this antibody can be used for staining of paraffin-embedded tissue sections fixed in neutral buffered formalin and is compatible with most commonly used histological fixatives. Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually.
Purity Detail:Affinity purified.
Formulation:Liquid. Ready-to-use solution in PBS containing 0.1% sodium azide and 1% BSA.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:+4°C
Regulatory Status:RUO - Research Use Only
Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use) Immunohistochemistry
Figure 1. Immunohistochemistry analysis of human melanoma skin tissue using Melanoma marker (human) mAb (HMB45) (Ready-To-Use), (Prod. No. ENZ-30930). Antibody is applied as is.
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Melanoma marker (human) monoclonal antibody (HMB45) (Ready-to-Use) Immunohistochemistry

Product Literature References

Sclerosing Epithelioid Fibrosarcoma of the Kidney: Clinicopathologic and Molecular Study of a Rare Neoplasm at a Novel Location: C.H. Ohlmann, et al.; Ann. Diagn. Pathol. 19, 221 (2015), Application(s): Immunohistochemistry, Abstract;
Comparison of HMB-45 monoclonal antibody and S-100 protein in the immunohistochemical diagnosis of melanoma: N.G. Ordonez, et al.; Am. J. Clin. Pathol. 90, 385 (1988), Abstract;
Immunohistochemical diagnosis of sinonasal melanoma, carcinoma, and neuroblastoma with monoclonal antibodies HMB-45 and anti-synaptophysin: M.R. Wick, et al.; Arch. Pathol. Lab. Med. 112, 616 (1988), Abstract;
Melanoma cell heterogeneity. A study of two monoclonal antibodies compared with S-100 protein in paraffin sections: P.H. Duray, et al.; Cancer 61, 2460 (1988), Abstract;
Recognition of malignant melanoma by monoclonal antibody HMB-45. An immunohistochemical study of 200 paraffin-embedded cutaneous tumors: M.R. Wick, et al.; J. Cutan. Pathol. 15, 201 (1988), Abstract;
Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes: A.M. Gown, et al.; Am. J. Pathol. 123, 195 (1986), Abstract; Full Text

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Melanoma marker (human) monoclonal antibody (HMB45) 

Purified from ascites., IHC (PS) | Print as PDF
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