Product Details
| Alternative Name: | CK1 |
| |
| Clone: | 34βB4 |
| |
| Host: | Mouse |
| |
| Isotype: | IgG1 |
| |
| Immunogen: | Keratin solubilized from human stratum corneum. |
| |
| UniProt ID: | P04264 |
| |
| Source: | Purified from ascites. |
| |
| Species reactivity: | Human
|
| |
| Specificity: | 34βB4 is specific for "high molecular weight" cytokeratin 1, 68 kDa, of "complex" epithelium. The antibody reacts with all squamous epithelium and squamous carcinomas. It does not react with adenocarcinomas of either simple epithelium (hepatoma) or ductal origin (breast, pancreas). |
| |
| Applications: | IHC (PS)
|
| |
| Recommended Dilutions/Conditions: | Immunohistochemistry (paraffin sections; for optimal results, fixation in alcohol-based fixatives, such as methacarn, is recommended. Pretreatment with proteolytic enzymes such as trypsin may be required when formalin-fixed sections are to be stained. Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually. |
| |
| Purity Detail: | Affinity purified. |
| |
| Formulation: | Liquid. Ready-to-use solution in PBS containing 0.1% sodium azide and 1% BSA. |
| |
| Shipping: | Blue Ice |
| |
| Long Term Storage: | +4°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Immunohistochemistry analysis of human skin tissue using Cytokeratin 1 (human), mAb (34βB4) at a dilution of 1:1.
Please mouse over
General Literature References
Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament proteins in normal human tissues: A.M. Gown & A.M. Vogel; Am. J. Pathol.
114, 309 (1984),
Abstract;
Full Text
Related Products
