Alternative Name: | Urokinase plasminogen activator receptor , CD87 |
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Clone: | R-4 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Native human uPAR. |
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UniProt ID: | Q03405 |
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Species reactivity: | Human
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Applications: | ELISA, Flow Cytometry, IHC, WB
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Purity Detail: | Protein A-affinity purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Short Term Storage: | +4°C |
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Scientific Background: | Urokinase plasminogen activator (uPA) is a serine protease. It converts the abundant proenzyme plasminogen to active plasmin, and plays a key role in cancer invasion and a variety of tissue remodelling processes such as wound healing, mammary gland involution and placental development. Elevated levels of uPA are associated with poor prognosis in many types of cancer. |
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Regulatory Status: | RUO - Research Use Only |
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