| Alternative Name: | Pulmonary surfactant-associated protein D, SP-D, PSP-D |
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| Clone: | 10B2 |
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| Host: | Mouse |
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| Isotype: | IgG2aκ |
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| Immunogen: | Purified human native SP-D from late pregnancy amniotic fluid. |
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| UniProt ID: | P35247 |
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| Species reactivity: | Human
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| Applications: | ELISA
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.14mM sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins, members of which possess an overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-D, and the serum proteins mannan-binding protein, conglutinin, and collectin-43, all of which bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals. |
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| Regulatory Status: | RUO - Research Use Only |
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