Product Specification
| Alternative Name: | Gp-340, Surfactant pulmonary-associated D-binding protein |
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| Clone: | 1G4 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Purified native human glycoprotein-340 from bronchioaveolar lavage from proteinosis patients. |
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| UniProt ID: | Q9UGM3 |
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| Species reactivity: | Human
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| Applications: | ELISA, IHC, WB
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Glycoprotein-340 belongs to the scavenger receptor superfamily which functions as a putative SP-D receptor. Gp-340 binds SP-D in a calcium dependent manner through a protein-protein interaction. Like SP-D, gp-340 is mainly found in lung tissue, and immunohistochemistry reveals high expression in alveolar macrophages. An identical protein is present in saliva (salivary agglutinin), and both forms are encoded by the gene DMBT1. |
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| Regulatory Status: | RUO - Research Use Only |
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For Research Use Only. Not for use in diagnostic procedures.
