Product Details
| Clone: | C17/5 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Purified human complement component C5a. |
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| UniProt ID: | P01031 |
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| Species reactivity: | Human
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| Applications: | ELISA, WB
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 10mM phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a(desArg). |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
A sensitive enzyme immunoassay for the quantitation of human C5a/C5a(desArg) anaphylatoxin using a monoclonal antibody with specificity for a neoepitope: M. Oppermann, et al.; Complement Inflamm.
8, 13 (1991),
Abstract;
