| Clone: | D10/4 |
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| Host: | Mouse |
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| Isotype: | IgG2aκ |
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| Immunogen: | Human complement factor D. |
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| UniProt ID: | P00746 |
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| Species reactivity: | Human
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| Specificity: | Recognizes human complement factor D in serum and plasma. |
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| Applications: | ELISA, WB
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| Application Notes: | Detects a band of ~25kDa by Western blot. |
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| Purity Detail: | Protein A purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment. |
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| Regulatory Status: | RUO - Research Use Only |
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