Alternative Name: | THBS1, TSP1 |
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Clone: | A65M |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Bovine extracellular matrix material from cultured corneal endothelial cells. |
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UniProt ID: | Q28178 |
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Species reactivity: | Human Bovine
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Applications: | ELISA, IHC, IP
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Application Notes: | Detects a band of ~150kDa by Western blot. |
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Purity Detail: | Protein A/G-affinity purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Short Term Storage: | +4°C |
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Scientific Background: | Thrombospondin 1 (TSP1) is a multidomain, multifunctional glycoprotein from platelets and certain vascular cells which is known to play an important role in cell-cell and cell-matrix interactions. TSP1 is a calcium-sensitive, disulfide-bonded trimer with a subunit molecular mass of 150kDa. TSP1 exists in different conformational states depending on the calcium ion concentration used in the purification buffers. |
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Regulatory Status: | RUO - Research Use Only |
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