| Alternative Name: | Basement membrane-specific heparan sulfate proteoglycan core protein, HSPG, PLC |
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| Clone: | A71 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Bovine corneal endothelial cells. |
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| UniProt ID: | P98160 (human) |
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| Species reactivity: | Human
Bovine
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| Applications: | ELISA, IHC, IP, FUNC
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| Application Notes: | Detects a band of ~400kDa by Western blot. |
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to permeability charateristics, serves as a substrate for vascular cells, and binds growth factors involved in vascular remodelling. |
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| Regulatory Status: | RUO - Research Use Only |
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