| Clone: | 99-72-18 |
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| Host: | Mouse |
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| Isotype: | IgG2bκ |
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| Immunogen: | Synthetic peptide consisting of the last 15 C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR). |
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| Source: | From culture supernatant. |
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| Species reactivity: | Human
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| Applications: | ELISA, IF, IHC (PS), IP, WB
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway. |
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| Regulatory Status: | RUO - Research Use Only |
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