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Complement component C3 (human) monoclonal antibody (F1-8)

 
BPD-CAM-008-01-04 400 µg 1,650.00 USD
 
BPD-CAM-008-01-1 1 mg 3,639.00 USD
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Product Details

Clone:F1-8
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Complement component 3 (C3) purified from human plasma.
 
UniProt ID:P01024
 
Source:From culture supernatant.
 
Species reactivity:Human
 
Specificity:Specific for human complement component 3 (C3/C3b/C3c).
 
Applications:ELISA, IP
Immunoaffinity chromatography
 
Purity Detail:Protein A/G-purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway.
 
Regulatory Status:RUO - Research Use Only
 

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