| Clone: | F1-8 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Complement component 3 (C3) purified from human plasma. |
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| UniProt ID: | P01024 |
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| Source: | From culture supernatant. |
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| Species reactivity: | Human
|
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| Specificity: | Specific for human complement component 3 (C3/C3b/C3c). |
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| Applications: | ELISA, IP
Immunoaffinity chromatography
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway. |
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| Regulatory Status: | RUO - Research Use Only |
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