| Alternative Name: | γENaC, Amiloride-sensitive sodium channel subunit γ |
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| Clone: | 5c2 |
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| Host: | Mouse |
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| Immunogen: | The inhibitorγ peptide from the human γENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human γENaC subunit. |
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| UniProt ID: | P51170 |
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| Species reactivity: | Human
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| Specificity: | Specific for the inhibitory tract of human γENaC subunit. |
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| Applications: | ELISA, IHC
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.14M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the γ-subunit and putative release of a 43-amino acid inhibitory tract from the γ-subunit ectodomain. |
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| Regulatory Status: | RUO - Research Use Only |
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