Alternative Name: | γENaC, Amiloride-sensitive sodium channel subunit γ |
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Clone: | 3c7 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | The inhibitorγ peptide from the human γENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human γENaC subunit. |
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UniProt ID: | P51170 |
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Source: | From culture supernatant. |
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Species reactivity: | Human
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Specificity: | Specific for the inhibitory tract of human γENaC subunit. |
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Applications: | ELISA, IHC (FS), IHC (PS), WB
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Purity Detail: | Protein A/G-purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the γ-subunit and putative release of a 43-amino acid inhibitory tract from the γ-subunit ectodomain. |
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Regulatory Status: | RUO - Research Use Only |
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