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Pregnancy-associated plasma protein A (human) monoclonal antibody (9)

 
BPD-BTE-004-09-04 400 µg 1,100.00 USD
 
BPD-BTE-004-09-1 1 mg 2,585.00 USD
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Product Details

Alternative Name:PAPP-A, Pappalysin-1, Insulin-like growth factor binding protein-4 protease
 
Clone:9
 
Host:Mouse
 
Isotype:IgG2bκ
 
Immunogen:Purified human PAPP-A.
 
UniProt ID:Q13219
 
GenBank ID:5069
 
Source:From culture supernatant.
 
Species reactivity:Human
 
Specificity:Specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A.
 
Applications:ELISA, IHC (FS), IHC (PS), WB
 
Purity Detail:Protein A/G-purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
 
Regulatory Status:RUO - Research Use Only
 
BTE 004-09  1  web
Figure 1: Immunohistochemical analysis of human placenta tissue using PAPP-A (human), mAb specific for human pregnancy associated plasma protein A (PAPP-A).
BTE 004-09  2  web
Figure 2: Immunohistochemical analysis of human placenta tissue using PAPP-A (human), mAb specific for human pregnancy associated plasma protein A (PAPP-A).
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BTE 004-09  1  web BTE 004-09  2  web

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