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Procollagen type IIA (NT) (human) monoclonal antibody (2)

BPD-BTE-003-02-04 400 µg 1,718.00 USD
BPD-BTE-003-02-1 1 mg 3,904.00 USD
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Product Details

Alternative Name:Collagen type II, Procollagen type II N-terminal propeptide, PIIANP
Immunogen:Recombinant PIIANP.
UniProt ID:P02458
GenBank ID:1280
Source:From culture supernatant.
Species reactivity:Human
Specificity:Epitope is located at the amino-terminal part of procollagen type IIA.
Applications:ELISA, IHC (PS)
Purity Detail:Protein A/G-purified.
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist, and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis, and the normal concentration in serum is approximately 30 ng/mL.
Regulatory Status:RUO - Research Use Only
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Figure 1: Immunohistochemical analysis of formalin-fixed, paraffin-embedded fetal bone anlage in the hand (around week 10) stained using Procollagen type IIA (NT).
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Figure 2: Immunohistochemical analysis of formalin-fixed, paraffin-embedded biopsy from a chondroblastoma, showing specific staining of tumor cells using Procollagen type IIA (NT) (human), mAb and developed with peroxidase-labeled goat anti-mouse Ig (blue color).
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