| Alternative Name: | Type I collagen, Procollagen type I C-terminal propeptide, PICP |
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| Clone: | 4 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Purified human PICP from second trimester amniotic fluid. |
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| UniProt ID: | P02452 |
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| GenBank ID: | 1277 |
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| Source: | From culture supernatant. |
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| Species reactivity: | Human
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| Specificity: | Specific for for native PICP from amniotic fluid. |
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| Applications: | ELISA
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Type I collagen is present in connective tissue and bone where it makes up about 90% of the organic matrix. Type I collagen is produced from type-I procollagen by the proteolytic cleavage of N- and C-telopeptides, which are released into the circulation. The propeptides can be measured in serum as markers of the production of type-I collagen. Elevated values of these propeptides are found in serum from patients with various metabolic or malignant bone diseases. Procollagen type I C-terminal propeptide (PICP) has a molecular mass of approximately 100kDa. Its normal concentration in serum depends on age and sex. |
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| Regulatory Status: | RUO - Research Use Only |
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