| Clone: | 46 |
| |
| Host: | Mouse |
| |
| Isotype: | IgG1κ |
| |
| Immunogen: | Synthetic oxyntomodulin 31-37 coupled to carrier. |
| |
| UniProt ID: | P01275 |
| |
| GenBank ID: | 2641 |
| |
| Source: | From culture supernatant. |
| |
| Species reactivity: | Human, Mouse, Rat
|
| |
| Specificity: | Specific for C-terminus of human oxyntomodulin. |
| |
| Crossreactivity: | Does not cross-react with glucagon. |
| |
| Applications: | ELISA
|
| |
| Purity Detail: | Protein A/G-purified. |
| |
| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
| |
| Shipping: | Blue Ice Not Frozen |
| |
| Long Term Storage: | +4°C |
| |
| Scientific Background: | Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
