Alternative Name: | Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Neutrophil lipocalin |
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Clone: | 33 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Human recombinant NGAL coupled to carrier and adsorbed to aluminum hydroxide gel. |
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UniProt ID: | P80188 |
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GenBank ID: | 3934 |
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Source: | From culture supernatant. |
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Species reactivity: | Human
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Applications: | ELISA
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Purity Detail: | Protein A/G-purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury. |
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Regulatory Status: | RUO - Research Use Only |
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