| Clone: | 20 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Synthetic full length oxyntomodulin coupled to carrier. |
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| UniProt ID: | P01275 |
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| GenBank ID: | 2641 |
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| Source: | From culture supernatant. |
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| Species reactivity: | Human
|
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| Crossreactivity: | Cross-reacts fully with glucagon. |
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| Applications: | ELISA
|
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |
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| Regulatory Status: | RUO - Research Use Only |
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