Alternative Name: | Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Neutrophil lipocalin |
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Clone: | 15 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant human NGAL. |
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UniProt ID: | P80188 |
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GenBank ID: | 3934 |
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Species reactivity: | Human
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Crossreactivity: | Does not cross-react with dog, pig, mouse or rat. |
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Applications: | ELISA, WB
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Purity Detail: | Protein A/G-purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) belongs to the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, and occurs as 25-kDa glycosylated single protein chain monomers which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury. |
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Regulatory Status: | RUO - Research Use Only |
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