| Alternative Name: | Bovine pancreatic trypsin inhibitor |
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| Clone: | 21 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Aprotinin from bovine lung. |
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| UniProt ID: | P00974 |
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| GenBank ID: | 404172 |
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| Source: | From culture supernatant. |
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| Species reactivity: | Bovine
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| Specificity: | Binds bovine aprotinin immobilized on a solid phase or free in solution. |
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| Applications: | ELISA, WB
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Aprotinin, also called bovine pancreatic trypsin inhibitor, is a single chain globular Kunitz-type serine proteinase inhibitor found in bovine pancreas, parotid gland and lung. It forms stable, enzymatically inactive complexes with trypsin, chymotrypsin, plasmin and kallikrein. Aprotinin has been used therapeutically as an antifibrinolytic agent under the name Trasylol (Bayer) to reduce blood loss during cardiopulmonary bypass surgery, but this use has been associated with an increased frequency of acute renal injury. |
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| Regulatory Status: | RUO - Research Use Only |
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