Alternative Name: | Ficolin-1, collectin |
|
Clone: | 1 |
|
Host: | Mouse |
|
Isotype: | IgG1κ |
|
Immunogen: | Synthetic peptide corresponding to aa 95-314 of human M-ficolin. |
|
UniProt ID: | O00602 |
|
Species reactivity: | Human
|
|
Applications: | ELISA, IHC
|
|
Purity Detail: | Protein A/G-affinity purified. |
|
Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
|
Shipping: | Blue Ice Not Frozen |
|
Short Term Storage: | +4°C |
|
Scientific Background: | M-Ficolin (Ficolin-1) is a non-serum protein expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria, and subsequently activates the lectin pathway. |
|
Regulatory Status: | RUO - Research Use Only |
|