Alternative Name: | GIP |
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Clone: | 4 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Synthetic peptide corresponding to the sequence of human gastric inhibitory. |
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UniProt ID: | P09681 |
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Species reactivity: | Human
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Applications: | ELISA, IHC
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Application Notes: | Detects a band of ~5kDa by Western blot. |
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Purity Detail: | Protein A/G-affinity purified. |
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Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Short Term Storage: | +4°C |
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Scientific Background: | Human gastric inhibitory polypeptide (GIP) is a 42-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2). |
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Regulatory Status: | RUO - Research Use Only |
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