| BPD-ABS-017-20-04 | 400 µg | 1,718.00 USD |  |
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| BPD-ABS-017-20-1 | 1 mg | 3,904.00 USD | |
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| Do you need bulk/larger quantities? | |||||
| Clone: | 20 |
| Host: | Mouse |
| Isotype: | IgG1κ |
| Immunogen: | Purified gelsolin from human plasma. |
| UniProt ID: | P06396 |
| GenBank ID: | 2934 |
| Source: | From culture supernatant. |
| Species reactivity: | Human |
| Applications: | ELISA, IF, IHC, WB |
| Purity Detail: | Protein A/G-purified. |
| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions. |
| Regulatory Status: | RUO - Research Use Only |
