| Alternative Name: | TAT |
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| Clone: | 22 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Thrombin-antithrombin (TAT) complexes |
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| UniProt ID: | P00734 (Prothrombin) |
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| GenBank ID: | 2147 |
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| Source: | From culture supernatant. |
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| Species reactivity: | Human
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| Specificity: | Specific for human Thrombin-antithrombin (TAT) complexes |
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| Applications: | ELISA, IHC
|
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| Purity Detail: | Protein A/G-purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Thrombin (Factor IIa) is an enzyme, a serine protease, which participates in blood clotting. It is formed when prothrombin (Factor II) is proteolytically cleaved to form thrombin, which is glycoprotein formed by two peptides chains of 36 and 259 amino acids. Thrombin converts soluble fibrinogen into insoluble strands of fibrin and is then neutralized by antithrombin in order to for a thrombin-antithrombin (TAT) complex. |
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| Regulatory Status: | RUO - Research Use Only |
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