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BAP1 (human), (recombinant) (His-tag)

BML-UW9855-0050 50 µg 239.00 USD
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Product Details

Alternative Name:BRCA1-associated protein 1, Ubiquitin C-terminal hydrolase BAP1
MW:84.1 kDa
Source:Produced in E. coli. Human BAP1 is fused at the N-terminus to a His-tag.
UniProt ID:Q92560
Formulation:Liquid. In 50mM Na-phosphate, pH 8.0, 300mM NaCl.
Purity:≥90% (SDS-PAGE)
Purity Detail:Purified by Ni-affinity chromatography.
Application Notes:Uses:
Deubiquitinylation assays using small molecule substrates (e.g. Ub-AMC) or ubiquitin-protein conjugates.
Studies of the tumor suppressor BRCA1, its interactions and associated proteins.
Shipping:Dry Ice
Long Term Storage:-80°C
Scientific Background:BAP1 is a BRCA1-associated ubiquitin C-terminal hydrolase. It shows homology to members of the ubiquitin C-terminal hydrolase (UCH) family and exhibits deubiquitinylating activity in vitro.
Regulatory Status:RUO - Research Use Only

Product Literature References

Spontaneous cellular and humoral tumor antigen responses in patients with uveal melanoma: P.L. Triozzi, et al.; Melanoma Res. 25, 510 (2015), Application(s): Added to PBMC cell culture, Abstract;

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