Source: | Produced in E.coli. |
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UniProt ID: | P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52) |
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Formulation: | Lyophilized from a water solution. |
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Application Notes: | For production of poly-ubiquitin chains via all lysines except lysine-48. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | [K48R]Ubiquitin, in which Lys48 has been mutated to Arg, is unable to form poly-ubiquitin chains via Lys48 linkages. The ability to form an active thioester at the C-terminus is preserved, allowing [K48R]ubiquitin to be transferred to the lysines of substrate proteins. |
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Regulatory Status: | RUO - Research Use Only |
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