Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. It shares the same binding site as rhizoxin and phomopsin A on porcine brain tubulin. Maytansine and its analogs cause extensive disassembly of the microtubule and totally prevent tubulin spiralization.
Product Details
| Formula: | C32H43ClN2O9 |
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| MW: | 635.1 |
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| CAS: | 66547-09-9 |
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| Purity: | ≥93% (HPLC) |
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| Appearance: | White to off-white crystalline solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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