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BML-279

PLD inhibitor
 
BML-ST372-0005 5 mg 99.00 USD
 
BML-ST372-0025 25 mg 303.00 USD
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Dual phospholipase D1/D2 (PLD1/PLD2) inhibitor in cellular assays (PLD1 IC50=8nM in Calu-1 cells; PLD2 IC50=42nM in HEK293-gfpPLD2 cells).

Product Specification

Alternative Name:N-[(1-[4-(2-Oxo-3H-benzimidazol-1-yl)-piperidin-1-yl]-ethyl]quinoline-3-carboxamide
 
Formula:C24H25N5O2
 
MW:415.5
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (25mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity: J.A. Lewis, et al.; Bioorg. Med. Chem. Lett. 19, 1916 (2009), Abstract;

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