Replaces Prod. #: ALX-300-142
A potent substrate analog inhibitor of snake venom PLA2 (IC50=2 µM). It inhibits human recombinant sPLA2 (IC50=0.9 µM) selectively over cPLA2.
Product Details
| Alternative Name: | 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine |
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| Formula: | C40H83N2O5PS |
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| MW: | 735.6 |
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| CAS: | 116457-99-9 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in DMSO, 100% ethanol or methanol. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. |
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| Handling: | Protect from moisture. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Secretory phospholipase A2 inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2: W.C. Hope, et al.; Agents Actions
39, C39 (1993),
Abstract;
The interaction of phospholipase A2 with phospholipid analogues and inhibitors: L. Yu, et al.; J. Biol. Chem.
265, 2657 (1990),
Abstract;
