A novel inhibitor of glucosylceramide synthase as well as glucosidase I and II. Inhibits glucosylceramide synthase without ceramide accumulation and cell death. It is a potent inhibitor of human immunodeficiency virus (HIV) replication and syncytium formation in vitro. Restores chloride current in epithelial CF cells.
Product Details
| Alternative Name: | Miglustat |
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| Formula: | C10H21NO4 . HCl |
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| MW: | 255.7 |
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| CAS: | 210110-90-0 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Determined by 1H-NMR and MS. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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