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3-O-Methyl-Sphingomyelin

Sphingomyelinase inhibitor
 
BML-SL225-0001 1 mg 149.00 USD
 
BML-SL225-0005 5 mg 602.00 USD
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3-O-Methyl-Sphingomyelin is a novel selective inhibitor of neutral sphingomyelinase, (Ki=37 µM). It is cell-permeable and does not inhibit acid sphingomyelinase.

Product Specification

Formula:C32H65N2O6P
 
MW:604.8
 
Purity:≥98% (TLC)
 
Identity:Determined by NMR.
 
Appearance:White to off-white solid.
 
Solubility:Soluble in ethanol (>25 mg/ml) or DMSO (20 mg/ml@50°C).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
Regulatory Status:RUO - Research Use Only
 
BML-SL225 structure
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BML-SL225 structure

Product Literature References

Ketamine, a Clinically Used Anesthetic, Inhibits Vascular Smooth Muscle Cell Proliferation via PP2A-Activated PI3K/Akt/ERK Inhibition: Y. Chang, et al.; Int. J. Mol. Sci. 18, 2545 (2017), Abstract; Full Text

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