| Alternative Name: | Dipeptidyl peptidase 8 |
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| MW: | 129 kDa |
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| Source: | Produced in insect cells. Active recombinant human DPP8 is fused at the N-terminus to a GST-tag. Produced in a baculovirus expression system. |
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| UniProt ID: | Q6V1X1 |
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| GenBank ID: | NM_197960 |
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| Formulation: | Liquid. In 40mM TRIS-HCl, pH 8.0, containing 110mM sodium chloride, 2.2mM potassium chloride, and 20% glycerol. |
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| Purity: | ≥70% (SDS-PAGE) |
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| Application Notes: | Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Use/Stability: | The enzyme is stable on ice for at least several hours. However, it is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay.
NOTE: When stored under the above conditions, this enzyme is stable at the concentration supplied, in its current storage buffer. Procedures such as dilution of the enzyme followed by refreezing could lead to loss of activity. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80°C. |
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| Scientific Background: | The biological function of DPP8 is not known, but it is found in the cytoplasm and may have roles in cell adhesion, migration, and apoptosis. This enzyme is related to DPPIV and is useful for specificity screening of DPPIV inhibitors to avoid toxic side effects. |
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| Regulatory Status: | RUO - Research Use Only |
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