| Alternative Name: | Phosphodiesterase 4A |
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| MW: | 37 kDa |
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| Source: | Produced in E. coli. Active catalytic domain of phosphodiesterase 4A. |
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| UniProt ID: | P27815 |
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| Formulation: | Liquid. In 20mM Tris-HCl, pH 8.0, containing 150mM NaCl, 2mM DTT. |
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| Application Notes: | Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | PDE4A is the primary cAMP metabolizing enzyme and is expressed in many inflammatory cells. Its inhibition attenuates the production of various inflammatory cell functions. It is inhibited by rolipram. |
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| Regulatory Status: | RUO - Research Use Only |
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