| Alternative Name: | Focal adhesion kinase |
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| MW: | 36 kDa |
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| Source: | Produced in insect cells. Active FAK (aa 411-686). Produced in a baculovirus expression system. |
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| UniProt ID: | Q05397 |
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| Formulation: | Liquid. In 25 mM Tris-HCl, pH 8.0, containing 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. |
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| Application Notes: | Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | FAK is involved in cell motility and it concentrates in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents such as fibronectin. It is also a major target for the tyrosine kinase Src and its deletion can block tumor formation and progression. |
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| Regulatory Status: | RUO - Research Use Only |
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