| MW: | 70 kDa |
| |
| Source: | Produced in insect cells. Full length human SPHK2 is fused at the N-terminus to a His-tag. Produced in a baculovirus expression system. |
| |
| UniProt ID: | Q9NRA0 |
| |
| Formulation: | Liquid. In 40mM Tris-HCl pH 8.0, 110 mM NaCl, 2/2 mM KCl, 3 mM DTT, 25 mM imidazole, and 20% glycerol. |
| |
| Shipping: | Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Scientific Background: | SPHK2 is one of two enzymes that can convert sphingosine to sphingosine-1-phosphate. SPHK2 has 45% identity and 80% similarity with SPHK1 and shares two large conserved regions. However, SPHK2 contains two extra domains, one internal and one at the N-terminus. SPHK2 is predominantly expressed in liver and heart. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
