Product Details
| Alternative Name: | Protein kinase C μ, Protein kinase D, PKD |
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| MW: | 131 kDa |
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| Source: | Produced in Sf9 insect cells. Active, full length protein kinase C mu (PKCµ, protein kinase D, PKD) is fused at the N-terminus to a GST-tag. Produced in a baculovirus expression system. |
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| UniProt ID: | Q15139 |
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| Application Notes: | Useful for Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | PKCµ is a novel member of the PKC family and contains a pleckstrin homology (PH) domain. PKCµ phosphorylates HDAC7, causing it to be exported out of the nucleus and relieving Nur77 repression. |
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| Technical Info/Product Notes: | Replacement for ADI-PPK-450 |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression: E. Pangou, et al.; Cell Rep.
35, 109129 (2021),
Abstract;
