EGFR is active but not autophosphorylated.
Product Details
| Alternative Name: | Epidermal growth factor receptor, EGFR |
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| MW: | 170 kDa |
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| Source: | Isolated from human A431 cells. |
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| UniProt ID: | P00533 |
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| Formulation: | Liquid. In 10% glycerol, 0.05% Triton X-100 buffer containing 5 mM EGF. |
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| Purity: | ≥90% (SDS-PAGE) |
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| Specific Activity: | One unit will add one pmol phosphate to angiotensin II per minute at pH 7.4 and 30°C |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O6-methylguanine-DNA methyltransferase with a double arm hybrid molecule: M. Rupp, et al.; Oncotarget
9, 35041 (2018),
Abstract;
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Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance: Y. Kabe, et al.; Nat. Commun.
7, 11030 (2016),
Abstract;
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Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting: S. Rao, et al.; PLoS One
10, e0117215 (2015),
Application(s): Assay,
Abstract;
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Comparative properties of caveolar and noncaveolar preparations of kidney Na+/K+-ATPase: L. Liu, et al.; Biochemistry
50, 8664 (2011),
Abstract;
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